Baclofen improves symptoms and reduces postprandial flow events in patients with rumination and supragastric belching

Blondeau K, Boecxstaens V, Rommel N, Farre R, Holvoet L, Boeckxstaens G, Tack J

Published in Clinical Gastroenterology and Hepatology, Vol. 10 (4), pp. 379-84

Key Findings

Baclofen 10 mg three times daily reduced supragastric belch frequency and reflux episodes.

GABA-B agonism can reduce belching when behavioural therapy fails.

Open-label, small sample, sedation side effects.

Year:2012

Sample Size:20

Duration:2 weeks

Quality Score:5/10

This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.