Impact of the Natural Compound Urolithin A on Health, Disease, and Aging
DAmico D, Andreux PA, Valdes P, Singh A, Rinsch C, Auwerx J
Published in Trends in Molecular Medicine
Methodology
Review of preclinical and clinical evidence on urolithin A, mitophagy and aging-related outcomes
Key Findings
Urolithin A stimulates mitophagy and improves muscle and metabolic markers across models, with early human trials showing safety and biomarker effects
Conclusions
Urolithin A is a promising mitophagy activator awaiting larger clinical outcome trials
Limitations
Review by authors affiliated with the developer; limited clinical endpoints
Supplements Studied
Urolithin A stimulates mitophagy and improves muscle and metabolic markers across models
Outcomes Measured
Urolithin A stimulates mitophagy and improves mitochondrial markers across models
Study Details
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