rct
    2024
    High Quality

    The effect of three years of vitamin D supplementation on erectile dysfunction: Results from the randomized placebo-controlled D-Health Trial

    Duarte Romero B, Waterhouse M, Baxter C, McLeod DSA, English DR, Armstrong BK

    Published in Clinical Nutrition ESPEN

    Methodology

    Exploratory analysis of the D-Health randomized placebo-controlled trial: 60,000 IU vitamin D or placebo monthly in Australian men aged 60-84, erectile dysfunction assessed after three years

    Key Findings

    Despite raising mean serum 25-hydroxy vitamin D from 76 to 106 nmol/L, three years of monthly high-dose vitamin D did not reduce the prevalence of erectile dysfunction compared with placebo.

    Conclusions

    Vitamin D supplementation does not improve erectile dysfunction in older, largely vitamin D-replete men.

    Limitations

    Exploratory secondary analysis, single self-reported ED question, older cohort with adequate baseline vitamin D.

    Supplements Studied

    Vitamin D
    Vitamin

    After three years of supplementation, the mean serum 25-hydroxy vitamin D concentration was 76 nmol/L... in the placebo group and 106 nmol/L... in the vitamin D group

    Related Health Concerns

    Study Details

    Year:2024
    Sample Size:8,920
    Duration:156 weeks
    Quality Score:9/10

    Disclosures

    Funding

    Australian National Health and Medical Research Council

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.