Safety and Efficacy of Black Cohosh and Red Clover for the Management of Vasomotor Symptoms: A Randomized Controlled Trial
Geller SE, Shulman LP, van Breemen RB, Banuvar S, Zhou Y, Epstein G, Hedayat S, Nikolic D, Krause EC, Piersen CE, Bolton JL, Pauli GF, Farnsworth NR
Published in Menopause
Key Findings
Neither red clover nor black cohosh reduced vasomotor symptoms significantly more than placebo over 12 months, while hormone therapy did.
Conclusions
Well-conducted trial found no benefit of red clover over placebo for hot flushes.
Limitations
Moderate sample size; high placebo response; single formulation.
Supplements Studied
Neither red clover nor black cohosh reduced vasomotor symptoms significantly more than placebo over 12 months.
Neither red clover nor black cohosh reduced vasomotor symptoms significantly more than placebo over 12 months, while hormone therapy did.
Outcomes Measured
Red clover did not outperform placebo for vasomotor symptoms over 12 months.
Related Health Concerns
Study Details
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