Pathogenesis, Clinical Signs and Treatment Recommendations in Brittle Nails: A Review
Chessa MA, Iorizzo M, Richert B, López-Estebaranz JL
Published in Dermatology and Therapy
Methodology
Narrative/clinical review of the pathogenesis, classification and treatment of nail fragility, covering oral supplementation, topical agents and management of underlying causes.
Key Findings
Nail brittleness affects up to 20% of the population, especially women over 50. In idiopathic nail fragility, biotin, trace elements and amino acids (especially cysteine) have been reported useful, alongside moisturizers and lacquers.
Conclusions
Optimal management requires treating the primary cause of brittle nails; oral supplementation plays a supporting role in idiopathic cases.
Limitations
Narrative review without pooled effect estimates; underlying supplementation trials are small and largely uncontrolled.
Supplements Studied
In idiopathic NF oral supplementation, vitamins (especially biotin, also known as vitamin B7), trace elements and amino acids (especially cysteine) have been reported to be useful.
Outcomes Measured
In idiopathic NF oral supplementation, vitamins (especially biotin, also known as vitamin B7), trace elements and amino acids (especially cysteine) have been reported to be useful.
Study Details
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Disclosures
Funding
Not reported
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.