Randomized, placebo-controlled, double-blinded study of prophylactic cranberries use in women with recurrent uncomplicated cystitis
Tsiakoulias E, Gravas S, Hadjichristodoulou C, Oikonomou KG, Kyritsi M
Published in World Journal of Urology
Methodology
12-month randomized, double-blind, placebo-controlled trial of high-dose proanthocyanidin cranberry extract (240 mg) in women with recurrent UTI
Key Findings
The number of UTIs was significantly lower with high-dose PAC cranberry extract than placebo over 12 months.
Conclusions
High-dose standardised proanthocyanidin extract offers meaningful prophylaxis in recurrent uncomplicated cystitis.
Limitations
Single-centre style recruitment; modest sample; product-specific PAC dose.
Supplements Studied
In response to intervention, the number of UTIs was significantly lower (Incidence rate ratio) in the cranberry group.
Study Details
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Disclosures
Funding
Not reported
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