Efficacy and safety of a hexanic extract of Serenoa repens (Permixon) for the treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia: systematic review and meta-analysis
Vela-Navarrete R, Alcaraz A, Rodriguez-Antolin A, Minana Lopez B, Fernandez-Gomez JM, Angulo JC, Castro Diaz D, Romero-Otero J, Brenes FJ, Carballido J, Molero Garcia JM, Fernandez-Pro Ledesma A, Cozar Olmos JM, Manasanch Dalmau J, Subirana Cachinero I, Herdman M, Ficarra V
Published in BJU International
Key Findings
The hexanic Serenoa repens extract reduced nocturia and improved peak urinary flow versus placebo, with effects on IPSS comparable to tamsulosin.
Conclusions
Extract-specific preparations may perform better than generic saw palmetto products.
Limitations
Restricted to one branded extract; several trials manufacturer sponsored.
Supplements Studied
The hexanic Serenoa repens extract reduced nocturia and improved peak urinary flow versus placebo.
Outcomes Measured
The hexanic Serenoa repens extract reduced nocturia and improved peak urinary flow versus placebo.
Study Details
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