rct
    2012
    High Quality

    A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults

    Chandrasekhar K, Kapoor J, Anishetty S

    Published in Indian Journal of Psychological Medicine, Vol. 34 (3), pp. 255-62

    Methodology

    Randomized double-blind placebo-controlled trial of high-concentration ashwagandha root extract in chronically stressed adults.

    Key Findings

    Ashwagandha reduced serum cortisol by roughly 28% and lowered stress scale scores versus placebo.

    Conclusions

    Ashwagandha lowers stress-axis output that drives sustained catecholamine tone.

    Limitations

    Single-centre Indian sample; catecholamines not measured directly.

    Supplements Studied

    Ashwagandha reduced serum cortisol by roughly 28% versus placebo

    Outcomes Measured

    Ashwagandha reduced serum cortisol by roughly 28% and lowered stress scale scores versus placebo

    Ashwagandha reduced perceived stress scores by 44% and serum cortisol by 27.9% compared with placebo

    Ashwagandha reduced serum cortisol by roughly 28% and lowered stress scale scores versus placebo.

    Study Details

    Year:2012
    Sample Size:64
    Duration:8 weeks
    Quality Score:7/10

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