Androgens and sexual function: a placebo-controlled, randomized, double-blind study of testosterone vs. dehydroepiandrosterone in men with sexual dysfunction and androgen deficiency
Morales A, Black A, Emerson L, Barkin J, Kuzmarov I, Day A
Published in Aging Male, Vol. 12 (4), pp. 104-12
Methodology
Randomised, double-blind, placebo-controlled trial: 86 men with sexual dysfunction and low testosterone and/or DHEA took oral testosterone undecanoate 80 mg twice daily, DHEA 50 mg twice daily, or placebo.
Key Findings
No significant differences in sexual interest or erectile function on the ADAM, IIEF, AMS or GAQ questionnaires. Serum DHEA rose in the DHEA group; PSA stayed stable in all groups.
Conclusions
Neither oral testosterone undecanoate nor DHEA showed a clinical benefit in men with hypoandrogenism and sexual dysfunction.
Limitations
Small groups; the abstract does not state the treatment duration; the testosterone arm may have been underdosed.
Supplements Studied
did not suggest a clinical benefit of OTU or DHEA supplementation
Related Health Concerns
Study Details
Access Study
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.