systematic_review
    2021

    Alternative Treatment Approaches to Small Intestinal Bacterial Overgrowth: A Systematic Review

    Nickles MA, Hasan A, Shakhbazova A, Wright S, Chambers CJ, Sivamani RK

    Published in J Altern Complement Med, Vol. 27 (2), pp. 108-119

    Methodology

    Systematic search of EMBASE, MEDLINE and Cochrane CENTRAL for human studies of probiotics, herbal preparations or diet to treat SIBO.

    Key Findings

    Eight studies qualified: five on probiotics, one on diet and two on herbal medicines. Studies were small, used non-standard formulations, and varied in breath-testing and symptom methods.

    Conclusions

    Preliminary evidence supports a role for alternative therapies, but large randomised placebo-controlled trials are needed.

    Limitations

    Few, small and heterogeneous studies; no pooled analysis was possible.

    Related Health Concerns

    Study Details

    Year:2021
    Quality Score:6/10

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