meta_analysis
    2012
    High Quality

    A systematic review and meta-analysis of α-lipoic acid in the treatment of diabetic peripheral neuropathy

    Han T, Bai J, Liu W

    Published in European Journal of Endocrinology, Vol. 167 (4), pp. 465-71

    Methodology

    Meta-analysis of RCTs of alpha-lipoic acid on neuropathic symptoms and nerve conduction in diabetes.

    Key Findings

    Alpha-lipoic acid improved total symptom score including burning pain and improved some nerve conduction measures.

    Conclusions

    Alpha-lipoic acid reduces burning neuropathic symptoms in diabetic neuropathy.

    Limitations

    Many trials used intravenous dosing; short duration; heterogeneity.

    Supplements Studied

    Alpha-lipoic acid improved neuropathic symptom scores including burning pain.

    Outcomes Measured

    Alpha-lipoic acid improved nerve conduction measures alongside symptom relief.

    Alpha-lipoic acid improved burning neuropathic pain symptoms in diabetic neuropathy.

    Related Health Concerns

    Study Details

    Year:2012
    Sample Size:653
    Quality Score:7/10

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