crossover
    2004
    High Quality

    Brief communication: sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite

    Spiegel K, Tasali E, Penev P, Van Cauter E

    Published in Annals of Internal Medicine

    Key Findings

    Two nights of 4-hour sleep reduced leptin 18 percent, raised ghrelin 28 percent and increased hunger ratings by 24 percent.

    Conclusions

    Sleep restriction is a reversible driver of excessive hunger.

    Limitations

    Small, short-term laboratory study in young men.

    Outcomes Measured

    Appetite Regulation

    Sleep curtailment lowered leptin, raised ghrelin and increased hunger ratings by 24 percent.

    Related Health Concerns

    Excessive Appetite

    Study Details

    Year:2004
    Sample Size:12
    Duration:1 weeks
    Quality Score:7/10

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