systematic_review
2008
High Quality
The Diagnosis of Cushing's Syndrome: An Endocrine Society Clinical Practice Guideline
Nieman LK, Biller BM, Findling JW
Published in Journal of Clinical Endocrinology & Metabolism
Methodology
Evidence-based clinical practice guideline developed from systematic literature review by an expert task force.
Key Findings
Recommends initial testing with urinary free cortisol, late-night salivary cortisol, or dexamethasone suppression, and exclusion of exogenous glucocorticoid exposure.
Conclusions
Cushing's syndrome requires biochemical confirmation before any treatment.
Limitations
Guideline recommendations vary in strength of underlying evidence.
Related Health Concerns
Study Details
Year:2008
Quality Score:9/10
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