systematic_review
    2008
    High Quality

    The Diagnosis of Cushing's Syndrome: An Endocrine Society Clinical Practice Guideline

    Nieman LK, Biller BM, Findling JW

    Published in Journal of Clinical Endocrinology & Metabolism

    Methodology

    Evidence-based clinical practice guideline developed from systematic literature review by an expert task force.

    Key Findings

    Recommends initial testing with urinary free cortisol, late-night salivary cortisol, or dexamethasone suppression, and exclusion of exogenous glucocorticoid exposure.

    Conclusions

    Cushing's syndrome requires biochemical confirmation before any treatment.

    Limitations

    Guideline recommendations vary in strength of underlying evidence.

    Related Health Concerns

    Study Details

    Year:2008
    Quality Score:9/10

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