rct
2016
High Quality
Effects of Vitex agnus and Flaxseed on cyclic mastalgia: A randomized controlled trial
Mirghafourvand M, Mohammad-Alizadeh-Charandabi S, Ahmadpour P, Javadzadeh Y
Published in Complementary Therapies in Medicine
Methodology
Three-arm placebo-controlled randomised trial: 25 g/day flaxseed powder, 3.2-4.8 mg/day Vitex agnus tablet, or double placebo
Key Findings
Breast pain improved significantly in both flaxseed and Vitex groups during the first and second months compared with placebo
Conclusions
Both flaxseed and Vitex agnus reduced cyclical mastalgia versus placebo
Limitations
Single-centre Iranian sample, short 2-month follow-up
Supplements Studied
Group II received daily 3.2-4.8mg V. agnus tablet and placebo of Flaxseed.
Related Health Concerns
Study Details
Year:2016
Sample Size:159
Duration:8 weeks
Quality Score:7/10
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