The Potential Role of Arginine Supplements on Erectile Dysfunction: A Systematic Review and Meta-Analysis
Rhim HC, Kim MS, Park YJ, Choi WS, Park HK, Kim HG
Published in The Journal of Sexual Medicine
Methodology
Systematic review and meta-analysis of 10 randomized controlled trials in 540 patients with mild to moderate erectile dysfunction comparing arginine supplements with placebo or no treatment
Key Findings
Arginine supplements at 1,500-5,000 mg significantly improved erectile dysfunction versus placebo or no treatment (OR 3.37, 95% CI 1.29-8.77, P=.01, I2=44).
Conclusions
Arginine supplementation may improve mild to moderate erectile dysfunction with a favorable safety profile.
Limitations
Small trials, heterogeneous doses and co-ingredients, limited to mild-to-moderate ED.
Supplements Studied
arginine supplements with dosage ranging from 1,500 to 5,000 mg significantly improved ED compared with placebo or no treatment (odds ratios, 3.37 [1.29, 8.77], P = .01, I2 = 44)
Related Health Concerns
Study Details
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Disclosures
Funding
Not reported
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.