systematic_review
    2022

    Urtica dioica: a review of its phytochemistry, pharmacology and clinical use

    Bhusal KK, Magar SK, Thapa R

    Published in Heliyon

    Key Findings

    Nettle root lignans inhibit sex hormone-binding globulin binding and 5-alpha-reductase in vitro, providing a mechanism for prostate effects; human safety data are reassuring at typical doses.

    Conclusions

    Plausible mechanism with good tolerability.

    Limitations

    Mostly preclinical evidence.

    Supplements Studied

    Nettle root lignans inhibit sex hormone-binding globulin binding and 5-alpha-reductase in vitro.

    Study Details

    Year:2022
    Quality Score:5/10

    Access Study

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    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.