meta_analysis
    2024
    High Quality

    Effect of multivitamin-mineral supplementation versus placebo on cognitive function: COSMOS-Clinic randomized clinical trial and meta-analysis

    Vyas CM, Manson JE, Sesso HD

    Published in American Journal of Clinical Nutrition

    Key Findings

    Pooled COSMOS cognitive substudies showed a small but significant benefit of multivitamins on global cognition in older adults, equivalent to roughly two years less ageing.

    Conclusions

    Modest cognitive signal is the strongest multivitamin finding to date.

    Limitations

    Small effect size, cognitive test surrogate.

    Supplements Studied

    Pooled COSMOS substudies showed a small but significant benefit on global cognition in older adults.

    Outcomes Measured

    Cognitive Function

    Global cognition improved modestly with multivitamin use in pooled COSMOS analyses.

    Related Health Concerns

    Cognitive Decline

    Study Details

    Year:2024
    Sample Size:5,000
    Duration:156 weeks
    Quality Score:8/10

    Access Study

    View on DOIView on PubMedOriginal Source

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.