rct
    2022
    High Quality

    Multivitamins in the prevention of cancer and cardiovascular disease: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial

    Sesso HD, Rist PM, Aragaki AK

    Published in American Journal of Clinical Nutrition

    Key Findings

    Daily multivitamin use for a median 3.6 years did not significantly reduce total invasive cancer or major cardiovascular events versus placebo.

    Conclusions

    No disease-prevention benefit in well-nourished adults.

    Limitations

    Relatively short follow-up for cancer endpoints.

    Supplements Studied

    Daily multivitamin use did not significantly reduce total invasive cancer or major cardiovascular events versus placebo.

    Related Health Concerns

    Cardiovascular Disease
    Cancer

    Study Details

    Year:2022
    Sample Size:21,442
    Duration:187 weeks
    Quality Score:9/10

    Access Study

    View on DOIView on PubMedOriginal Source

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.