Does Beano Prevent Gas? A Double-Blind Crossover Study of Oral Alpha-Galactosidase to Treat Dietary Oligosaccharide Intolerance
Ganiats TG, Norcross WA, Halverson AL, Burford PA, Palinkas LA
Published in Journal of Family Practice
Methodology
Double-blind crossover trial of oral alpha-galactosidase versus placebo taken with a meal of meatless chili in 19 volunteers, with symptom and flatus-frequency diaries.
Key Findings
Alpha-galactosidase significantly reduced flatus frequency compared with placebo, but did not significantly change bloating, abdominal pain or overall symptom severity scores.
Conclusions
Alpha-galactosidase reduces gas production from oligosaccharide-rich meals, with limited effect on other digestive symptoms.
Limitations
Very small sample; single test meal; older study; subjective diary outcomes.
Supplements Studied
Alpha-galactosidase significantly reduced flatus frequency compared with placebo, without significantly changing bloating or pain.
Outcomes Measured
Alpha-galactosidase did not significantly change bloating or overall symptom severity scores.
Related Health Concerns
Study Details
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