rct
2006
Copper-molybdenum antagonism and its clinical relevance: tetrathiomolybdate in Wilson disease
Brewer GJ, Askari F, Lorincz MT
Published in Archives of Neurology
Key Findings
Tetrathiomolybdate preserved neurological function better than trientine in newly diagnosed neurologic Wilson disease by depleting copper.
Conclusions
Illustrates that excess molybdenum antagonises copper.
Limitations
Small trial in a rare disease.
Supplements Studied
Molybdenum
Mineral
Tetrathiomolybdate depletes copper, illustrating the antagonism between excess molybdenum and copper status.
Copper
Mineral
Tetrathiomolybdate preserved neurological function better than trientine in newly diagnosed neurologic Wilson disease by depleting copper.
Study Details
Year:2006
Sample Size:48
Duration:32 weeks
Quality Score:6/10
Access Study
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