rct
    2009

    A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: immunological effects

    Deng G, Lin H, Seidman A

    Published in Journal of Cancer Research and Clinical Oncology

    Key Findings

    Oral maitake polysaccharide produced both immune-stimulatory and immune-suppressive measurable effects, with no dose-limiting toxicity.

    Conclusions

    Immunomodulation is real but bidirectional and of unclear clinical value.

    Limitations

    Phase I/II, no clinical outcome endpoints.

    Supplements Studied

    Oral maitake extract produced both immune-stimulatory and immune-suppressive measurable effects without dose-limiting toxicity.

    Outcomes Measured

    Immune Function

    Maitake extract produced measurable but bidirectional immunological effects in breast cancer patients.

    Related Health Concerns

    Breast Cancer
    Cancer

    Study Details

    Year:2009
    Sample Size:34
    Duration:3 weeks
    Quality Score:5/10

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