A Randomized Multicenter Study of Gamolenic Acid (Evening Primrose Oil) With and Without Antioxidant Vitamins and Minerals in the Management of Mastalgia
Goyal A, Mansel RE
Published in Breast Journal
Methodology
Randomized double-blind placebo-controlled multicentre factorial trial of gamolenic acid, with or without antioxidants, for 4 months in 555 women with moderate to severe mastalgia.
Key Findings
Pain scores improved in all groups, with no significant difference between gamolenic acid and placebo control oil.
Conclusions
Evening primrose oil was no better than placebo for cyclical or non-cyclical breast pain.
Limitations
Placebo oil may not be fully inert; high placebo response; four-month duration.
Supplements Studied
Pain scores improved in all groups, with no significant difference between gamolenic acid and placebo control oil.
Related Health Concerns
Study Details
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