rct
    2015
    High Quality

    Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial

    Chew EY, Clemons TE, Agron E

    Published in JAMA

    Key Findings

    Lutein/zeaxanthin supplementation had no significant effect on cognitive decline over five years in older adults.

    Conclusions

    Null result for cognition.

    Limitations

    Older AMD population, cognitive endpoints secondary.

    Supplements Studied

    Zeaxanthin
    Compound

    Lutein/zeaxanthin supplementation had no statistically significant effect on cognitive function over five years in AREDS2 participants.

    Lutein
    Compound

    Lutein/zeaxanthin supplementation had no significant effect on cognitive decline over five years.

    Lutein/zeaxanthin supplementation had no significant effect on cognitive decline over five years in older adults.

    Outcomes Measured

    Cognitive Function

    Lutein/zeaxanthin had no significant effect on cognitive decline over five years.

    Related Health Concerns

    Cognitive Decline

    Study Details

    Year:2015
    Sample Size:3,741
    Duration:260 weeks
    Quality Score:9/10

    Access Study

    View on DOIView on PubMedOriginal Source

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.