systematic_review
    2010
    High Quality

    Effects of tryptophan loading on human cognition, mood, and sleep

    Silber BY, Schmitt JAJ

    Published in Neuroscience & Biobehavioral Reviews

    Key Findings

    Tryptophan loading consistently increases subjective sleepiness and reduces sleep latency, but cognitive effects are inconsistent and sometimes impairing.

    Conclusions

    Sedation is the most reliable effect.

    Limitations

    Heterogeneous acute loading protocols.

    Supplements Studied

    L-Tryptophan
    Amino Acid

    Tryptophan loading reliably increases subjective sleepiness and shortens sleep latency, with inconsistent cognitive effects.

    Outcomes Measured

    Cognitive Function

    Cognitive effects of tryptophan loading were inconsistent and sometimes impairing.

    Related Health Concerns

    Insomnia

    Study Details

    Year:2010
    Quality Score:7/10

    Access Study

    View on DOIView on PubMedOriginal Source

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.