rct
    1979

    DL-phenylalanine versus imipramine: a double-blind controlled study

    Beckmann H, Athen D, Olteanu M

    Published in Archiv fur Psychiatrie und Nervenkrankheiten

    Key Findings

    DL-phenylalanine produced antidepressant effects comparable to imipramine over 30 days in depressed inpatients.

    Conclusions

    Historical positive signal, never replicated in modern trials.

    Limitations

    Small, no placebo arm, 1970s methodology.

    Supplements Studied

    L-Phenylalanine
    Amino Acid

    DL-phenylalanine produced antidepressant effects comparable with imipramine in a small 1970s inpatient trial.

    Related Health Concerns

    Depression

    Study Details

    Year:1979
    Sample Size:40
    Duration:4 weeks
    Quality Score:3/10

    Access Study

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    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.