systematic_review
    2017
    High Quality

    Key European guidelines for the diagnosis and management of patients with phenylketonuria

    van Spronsen FJ, van Wegberg AM, Ahring K

    Published in The Lancet Diabetes & Endocrinology

    Key Findings

    Phenylalanine intake must be strictly restricted lifelong in phenylketonuria because elevated blood phenylalanine is neurotoxic.

    Conclusions

    Absolute contraindication for phenylalanine supplements in PKU.

    Limitations

    Guideline synthesis, not an efficacy trial.

    Supplements Studied

    L-Phenylalanine
    Amino Acid

    Phenylalanine intake must be strictly restricted lifelong in phenylketonuria because elevated blood phenylalanine is neurotoxic.

    Study Details

    Year:2017
    Quality Score:9/10

    Access Study

    View on DOIView on PubMedOriginal Source

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.