cohort
    2018
    High Quality

    Spermidine intake and mortality risk: a prospective population-based study

    Kiechl S, Pechlaner R, Willeit P, Notdurfter M, Paulweber B, Willeit J

    Published in American Journal of Clinical Nutrition

    Methodology

    Prospective cohort study relating dietary spermidine intake to 20-year all-cause mortality with independent validation cohorts.

    Key Findings

    Higher dietary spermidine intake was associated with lower all-cause mortality, an effect comparable to a 5-year younger age.

    Conclusions

    Observational data link spermidine intake to longer survival, but causality remains unproven.

    Limitations

    Observational design with residual confounding; dietary intake estimated from questionnaires.

    Supplements Studied

    Spermidine
    Compound

    Higher dietary spermidine intake was associated with lower all-cause mortality

    Outcomes Measured

    Higher dietary spermidine intake was associated with lower all-cause mortality

    Study Details

    Year:2018
    Sample Size:829
    Duration:1040 weeks
    Quality Score:7/10

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.