crossover
    2004

    Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis

    Kennedy DO, Little W, Scholey AB

    Published in Psychosomatic Medicine

    Key Findings

    A single 600 mg dose of Melissa officinalis reduced induced stress ratings and increased calmness, with impaired performance on some tasks at higher doses.

    Conclusions

    Acute anxiolytic effect with possible dose-dependent sedation.

    Limitations

    Healthy volunteers, laboratory stressor only.

    Supplements Studied

    A single dose of Melissa officinalis increased self-rated calmness during a laboratory stressor, with task performance impaired at the higher dose.

    Study Details

    Year:2004
    Sample Size:18
    Duration:1 weeks
    Quality Score:5/10

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