systematic_review
    2023
    High Quality

    Natural products for the treatment of denture stomatitis: A systematic review

    Inácio Silveira DQ, Lia EN, Massignan C, Stefani CM

    Published in The Journal of Prosthetic Dentistry

    Methodology

    PROSPERO-registered systematic review of 17 studies across 11 databases comparing topical natural substances with conventional antifungals for denture stomatitis, synthesised without meta-analysis

    Key Findings

    Uncaria tomentosa, alongside propolis, green tea, ginger and other natural products, appeared to have efficacy and safety similar to nystatin or miconazole, but overall evidence certainty was low.

    Conclusions

    Natural products including cat's claw may be comparable to conventional antifungals for denture stomatitis, though evidence quality is insufficient for firm recommendations.

    Limitations

    Heterogeneous small trials; narrative synthesis without pooled effect sizes; low certainty of evidence.

    Supplements Studied

    Propolis, green tea, ginger, Zataria multiflora, chitosan, garlic, Artemisia, Schinus terebinthifolius Raddi, Uncaria tomentosa, Punica granatum, and Ricinus communis appeared to have similar efficacy and safety when compared with nystatin or miconazole.

    Study Details

    Year:2023
    Quality Score:7/10

    Disclosures

    Funding

    Not specified

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.