systematic_review
    2019

    Lactoferrin: structure, function, denaturation and digestion

    Wang B, Timilsena YP, Blanch E

    Published in Critical Reviews in Food Science and Nutrition

    Key Findings

    Reviews iron-binding, antimicrobial and immunomodulatory functions and loss of activity with heat processing and digestion.

    Conclusions

    Delivery form materially affects lactoferrin bioactivity.

    Limitations

    Mechanistic review, not clinical.

    Supplements Studied

    Lactoferrin
    Compound

    Lactoferrin binds iron and exerts antimicrobial and immunomodulatory activity, but is substantially denatured by heat and gastric digestion.

    Outcomes Measured

    Iron Absorption

    Lactoferrin binds iron with high affinity, but heat processing and digestion reduce its activity.

    Study Details

    Year:2019
    Quality Score:6/10

    Access Study

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    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.