Nano-emodin mediated photodynamic therapy for wound healing of donor site after free gingival graft: a parallel clinical trial
Yaghobee S, Pourhajibagher M, Bahrami R, Isaabadi M
Published in Photodiagnosis and Photodynamic Therapy
Methodology
Single-centre, parallel, two-blind randomised controlled trial in 53 patients undergoing free gingival graft surgery, comparing nano-emodin gel plus 450 nm LED photodynamic therapy, nano-emodin gel alone and placebo gel applied immediately and 48 hours after surgery
Key Findings
Topical nano-emodin mediated photodynamic therapy is the only randomised human evidence available for emodin, and it addresses local wound healing rather than any oral supplement use.
Conclusions
Human emodin data are confined to a small topical dental trial; no oral supplementation RCTs exist.
Limitations
Small single-centre trial; topical nano-formulation not comparable to oral emodin; short follow-up.
Supplements Studied
The study employed a single-center, parallel, two-blind, randomized, controlled trial design. A total of 53 patients requiring FGG treatment were randomly assigned to one of three groups.
Study Details
Access Study
Disclosures
Funding
Not reported
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.