systematic_review
2018
High Quality
Idiopathic environmental intolerances: a systematic review
Rossi S, Pitidis A
Published in Journal of Occupational and Environmental Medicine
Methodology
Systematic review of epidemiology, mechanisms and management of idiopathic environmental intolerance.
Key Findings
No consistent toxicological or immunological marker has been identified; central sensitisation and conditioning models best fit the evidence, and management is supportive.
Conclusions
Chemical sensitivity lacks a validated biomarker; no supplement protocol is evidence-based.
Limitations
Heterogeneous case definitions across studies.
Related Health Concerns
Study Details
Year:2018
Sample Size:3,000
Quality Score:7/10
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