observational
    2009
    High Quality

    Cold-activated brown adipose tissue in healthy men

    van Marken Lichtenbelt WD, et al

    Published in N Engl J Med

    Key Findings

    Cold exposure activated brown adipose tissue in 23 of 24 healthy men; activity was markedly lower in obese participants.

    Conclusions

    BAT is present and cold-activatable in most adults and inversely related to adiposity.

    Limitations

    Small sample, imaging-based surrogate of thermogenesis.

    Outcomes Measured

    Brown Fat Activation
    Primary

    Cold exposure activated brown adipose tissue in 23 of 24 healthy men; activity was markedly lower in obese participants.

    Cold Tolerance

    Cold exposure activated brown adipose tissue in 23 of 24 healthy men; activity was markedly lower in obese participants.

    Study Details

    Year:2009
    Sample Size:24
    Quality Score:7/10

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