rct
2016
High Quality
Randomized trial of introduction of allergenic foods in breast-fed infants
Perkin MR, Logan K, Tseng A, Raji B, Ayis S, Peacock J, Lack G
Published in New England Journal of Medicine
Key Findings
Early introduction of six allergenic foods did not reduce food allergy in the intention-to-treat analysis, though a per-protocol effect was seen for peanut and egg.
Conclusions
Benefit of early introduction depends heavily on adherence to sufficient allergen dose.
Limitations
Low adherence in the early-introduction group limits interpretation.
Related Health Concerns
Study Details
Year:2016
Sample Size:1,303
Duration:156 weeks
Quality Score:9/10
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