rct
    2016
    High Quality

    Randomized trial of introduction of allergenic foods in breast-fed infants

    Perkin MR, Logan K, Tseng A, Raji B, Ayis S, Peacock J, Lack G

    Published in New England Journal of Medicine

    Key Findings

    Early introduction of six allergenic foods did not reduce food allergy in the intention-to-treat analysis, though a per-protocol effect was seen for peanut and egg.

    Conclusions

    Benefit of early introduction depends heavily on adherence to sufficient allergen dose.

    Limitations

    Low adherence in the early-introduction group limits interpretation.

    Related Health Concerns

    Study Details

    Year:2016
    Sample Size:1,303
    Duration:156 weeks
    Quality Score:9/10

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