rct
    2006

    Estrogenic Activity of Standardized Extract of Angelica sinensis and Matricaria recutita in Menopausal Women: A Randomized Trial

    Circosta C, De Pasquale R, Palumbo DR, Samperi S, Occhiuto F

    Published in Journal of Ethnopharmacology

    Methodology

    Twelve-week randomised placebo-controlled trial of a standardised Angelica sinensis plus Matricaria recutita combination in 55 menopausal women with hot flushes.

    Key Findings

    The combination reduced hot flush frequency and intensity substantially more than placebo, with no change in endometrial thickness or hormone levels.

    Conclusions

    A dong quai plus chamomile combination reduced hot flushes, though the contribution of Angelica sinensis alone is unclear.

    Limitations

    Small sample; combination product; short duration; single centre.

    Supplements Studied

    The combination reduced hot flush frequency and intensity substantially more than placebo.

    The combination reduced hot flush frequency and intensity substantially more than placebo, with no change in endometrial thickness or hormone levels.

    Outcomes Measured

    Menopause Symptom Relief

    The combination reduced hot flush frequency and intensity substantially more than placebo.

    Related Health Concerns

    Menopause
    Hot Flashes

    Study Details

    Year:2006
    Sample Size:55
    Duration:12 weeks
    Quality Score:5/10

    Access Study

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