The Metabolism and Potential Bioactivity of Chlorophyll and Metallo-chlorophyll Derivatives in the Gastrointestinal Tract
Zhong S, Bird A, Kopec RE
Published in Molecular Nutrition & Food Research
Methodology
Review of absorption, distribution, metabolism and excretion of chlorophyll and metallo-chlorophyll derivatives, plus toxin-binding activity
Key Findings
Chlorophyll derivatives are poorly absorbed intact; most bioactivity occurs in the gut lumen through binding of dioxins, heterocyclic amines, PAHs and aflatoxin during digestion.
Conclusions
Benefits are best framed as gut-level toxin binding rather than systemic "detoxification" or blood-building effects.
Limitations
Significant gaps remain in human absorption and metal-delivery data; heterogeneous in vitro methods.
Supplements Studied
This review also detail chlorophyll and metallo-chlorophyll toxin binding properties which largely occur during digestion, focusing on toxins including dioxins, heterocyclic aromatic amines, polyaromatic hydrocarbons, and aflatoxin.
Study Details
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Disclosures
Funding
Not reported
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.