rct
    2015
    High Quality

    Acetaminophen for fever in critically ill patients with suspected infection

    Young P, Saxena M, Bellomo R, Freebairn R, Hammond N, van Haren F, Holliday M

    Published in New England Journal of Medicine

    Key Findings

    Acetaminophen lowered temperature but did not affect ICU-free days, mortality or other patient-centred outcomes versus placebo.

    Conclusions

    Suppressing fever itself does not improve outcomes in infection; treat for comfort.

    Limitations

    ICU population; limited generalisability to outpatient fever.

    Related Health Concerns

    Fever

    Study Details

    Year:2015
    Sample Size:700
    Duration:4 weeks
    Quality Score:9/10

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