Efficacy of vitamin B-6 in the treatment of premenstrual syndrome: systematic review
Wyatt KM, Dimmock PW, Jones PW, Shaughn OBrien PM
Published in BMJ
Abstract
Systematic review of randomised placebo-controlled trials of vitamin B-6 for premenstrual syndrome.
Key Findings
Pooled odds ratio favoured vitamin B-6 over placebo for overall premenstrual symptoms, though included trials were of low methodological quality.
Conclusions
Doses up to 100 mg/day of vitamin B-6 are likely to benefit premenstrual symptoms, but the evidence base is weak.
Limitations
Included trials were small and of poor quality; publication bias possible.
Supplements Studied
Pooled odds ratio favoured vitamin B-6 over placebo for overall premenstrual symptoms, though included trials were of low methodological quality.
Outcomes Measured
Vitamin B6 was more effective than placebo for overall premenstrual symptoms and premenstrual depression, but the trials were of low methodological quality
Vitamin B6 was more effective than placebo for overall premenstrual symptoms, but the trials were of low methodological quality
Related Health Concerns
Study Details
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