Higher spermidine intake is linked to lower mortality: a prospective population-based study
Kiechl S, Pechlaner R, Willeit P, Notdurfter M, Paulweber B, Willeit K, Werner P, Ruckenstuhl C, Iglseder B, Weger S, Mairhofer B, Gartner M, Kedenko L, Chmelikova M, Stekovic S, Stuppner H, Oberhollenzer F, Kroemer G, Mayr M, Eisenberg T, Tilg H, Madeo F, Willeit J
Published in American Journal of Clinical Nutrition
Methodology
Prospective population-based Bruneck study relating dietary spermidine intake to 20-year all-cause mortality in 829 participants.
Key Findings
Mortality was inversely associated with spermidine intake; the difference between top and bottom tertiles was comparable to several years of younger age.
Conclusions
Higher dietary spermidine intake is associated with reduced all-cause mortality.
Limitations
Observational design; dietary polyamine intake correlates with overall healthy eating patterns.
Supplements Studied
Higher dietary spermidine intake is associated with reduced all-cause mortality.
Study Details
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