Dietary supplement interactions with antiretrovirals: a systematic review
Jalloh MA, Gregory PJ, Hein D, Risoldi Cochrane Z, Rodriguez A
Published in International Journal of STD & AIDS
Methodology
Systematic review of 28 pharmacokinetic studies and case series/reports evaluating interactions between dietary supplements and antiretroviral drugs
Key Findings
Cat's claw was found to significantly increase levels of antiretrovirals, and patients taking both should be monitored for adverse effects.
Conclusions
Cat's claw carries a clinically relevant drug-interaction risk through raised antiretroviral drug levels.
Limitations
Based largely on small pharmacokinetic studies and case reports rather than controlled trials; interaction magnitude not quantified.
Supplements Studied
Cat's claw and evening primrose oil were found to significantly increase the levels of antiretrovirals and patients should be monitored for adverse effects while taking these dietary supplements.
Study Details
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Disclosures
Funding
Not specified
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.