rct
    2012

    Safety and Efficacy Profile of Echinacea purpurea to Prevent Common Cold Episodes: A Randomized, Double-Blind, Placebo-Controlled Trial

    Jawad M, Schoop R, Suter A, Klein P, Eccles R

    Published in Evidence-Based Complementary and Alternative Medicine

    Methodology

    Four-month randomized double-blind placebo-controlled trial of Echinacea purpurea extract (2400 mg/day) for cold prevention in 755 healthy adults.

    Key Findings

    The Echinacea group had fewer cold episodes and days of illness and reduced need for rescue medication, with adverse event rates comparable to placebo.

    Conclusions

    Long-term prophylactic Echinacea purpurea use modestly reduced cold episodes and was well tolerated.

    Limitations

    Single proprietary product; manufacturer-funded; self-reported episodes.

    Supplements Studied

    The Echinacea group had fewer cold episodes and days of illness and reduced need for rescue medication.

    Outcomes Measured

    The Echinacea group had fewer cold episodes and days of illness over four months.

    Study Details

    Year:2012
    Sample Size:755
    Duration:16 weeks
    Quality Score:6/10

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