Glycine supplementation and collagen synthesis: dietary glycine is a conditionally essential nutrient for collagen formation

Melendez-Hevia E, De Paz-Lugo P, Cornish-Bowden A, Cardenas ML

Published in Journal of Biosciences

Methodology

Metabolic modelling and biochemical analysis of endogenous glycine synthesis versus collagen demand in humans

Endogenous glycine synthesis falls roughly 10 g/day short of the amount required for optimal collagen turnover.

Dietary or supplemental glycine is likely required to fully support collagen synthesis.

Theoretical metabolic analysis rather than a clinical trial.

Amino Acid

The capacity of glycine synthesis in humans is insufficient to meet the metabolic demand for collagen synthesis, a deficit of about 10 g per day.

Year:2009

Quality Score:5/10

This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.