Efficacy of adjuvant immunochemotherapy with polysaccharide K for patients with curatively resected colorectal cancer: a meta-analysis of centrally randomized controlled clinical trials
Sakamoto J, Morita S, Oba K
Published in Cancer Immunology, Immunotherapy
Methodology
Meta-analysis of three centrally randomized controlled trials of adjuvant PSK from Trametes versicolor after curative colorectal cancer resection
Key Findings
Adjuvant PSK improved overall survival and disease-free survival compared with chemotherapy alone
Conclusions
Adjuvant PSK immunochemotherapy improves survival after curative resection of colorectal cancer
Limitations
Older Japanese trials; open-label designs; limited generalizability
Supplements Studied
Adjuvant PSK improved overall and disease-free survival after curative colorectal cancer resection
Outcomes Measured
Adjuvant PSK immunochemotherapy improved survival, consistent with immune-mediated benefit
Related Health Concerns
Study Details
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