meta_analysis
    2025
    High Quality

    The effects of beta-hydroxy-beta-methylbutyrate supplementation in patients with sarcopenia: a systematic review and meta-analysis

    Gu WT, Zhang LW, Wu FH, Wang S

    Published in Archives of Gerontology and Geriatrics

    Methodology

    Systematic review and meta-analysis of randomised trials of HMB supplementation in patients with sarcopenia

    Key Findings

    HMB significantly increased muscle mass but effects on muscle strength and physical performance were small and inconsistent.

    Conclusions

    HMB helps preserve muscle mass in sarcopenia while functional gains remain unproven.

    Limitations

    Heterogeneous co-interventions with protein and exercise.

    Supplements Studied

    HMB
    Amino Acid

    HMB significantly increased muscle mass but effects on muscle strength and physical performance were small and inconsistent.

    Outcomes Measured

    HMB increased muscle mass but effects on strength and physical performance were small and inconsistent.

    Related Health Concerns

    Study Details

    Year:2025
    Sample Size:800
    Duration:12 weeks
    Quality Score:8/10

    This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.