Ashwagandha (Withania somnifera) and stress hormone responses: a randomized double-blind placebo-controlled study
Chandrasekhar K, Kapoor J, Anishetty S
Published in Indian Journal of Psychological Medicine
Methodology
Randomized double-blind placebo-controlled trial of high-concentration ashwagandha root extract in chronically stressed adults.
Key Findings
Ashwagandha reduced serum cortisol by roughly 28% and lowered stress scale scores versus placebo.
Conclusions
Ashwagandha lowers stress-axis output that drives sustained catecholamine tone.
Limitations
Single-centre Indian sample; catecholamines not measured directly.
Supplements Studied
Ashwagandha reduced serum cortisol by roughly 28% versus placebo
Outcomes Measured
Ashwagandha reduced serum cortisol by roughly 28% and lowered stress scale scores versus placebo
Ashwagandha reduced perceived stress scores by 44% and serum cortisol by 27.9% compared with placebo
Ashwagandha reduced serum cortisol by roughly 28% and lowered stress scale scores versus placebo.
Study Details
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