rct
    2006

    Treatment of non-cardiac chest pain: a controlled trial of hypnotherapy

    Jones H, et al.

    Published in Gut

    Methodology

    Randomised controlled trial comparing 12 sessions of gut-directed hypnotherapy with supportive listening plus placebo medication over 17 weeks in patients with non-cardiac chest pain, with global symptom improvement as primary endpoint.

    Key Findings

    In 28 patients with non-cardiac chest pain, 12 sessions of gut-directed hypnotherapy produced significantly greater global improvement in pain (80% vs 23% of controls) and reduced pain intensity and medication use compared with supportive listening plus placebo medication, though quality of life scores changed little.

    Conclusions

    Hypnotherapy substantially improved symptoms in refractory non-cardiac chest pain, supporting a brain-gut treatment approach.

    Limitations

    Small single-centre trial, therapist attention could not be fully matched, blinding of participants impossible, outcomes largely self-reported, and durability beyond the treatment period not established.

    Related Health Concerns

    Study Details

    Year:2006
    Sample Size:28
    Duration:17 weeks
    Quality Score:6/10

    Disclosures

    Funding

    Academic/NHS research funding (UK)

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