Efficacy of Omega-3 Intake in Managing Dry Eye Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Wang WX, Ko ML
Published in Journal of Clinical Medicine
Methodology
Meta-analysis of 19 RCTs (2013-2023) of omega-3 fatty acid supplementation in dry eye disease, assessing symptom scores, tear break-up time, Schirmer test, osmolarity and corneal staining.
Key Findings
Omega-3 supplementation significantly improved dry eye symptoms (Hedges g = -1.047; p < 0.001) and tear film measures versus control.
Conclusions
Omega-3 intake improves symptoms and tear film stability in dry eye disease, a common driver of screen-related eye strain.
Limitations
Substantial heterogeneity; varied omega-3 doses, formulations and etiologies; several trials at risk of bias.
Supplements Studied
Patients given omega-3 treatment demonstrated more significant improvements in dry eye symptoms (Hedges' g = -1.047; p < 0.001)
Related Health Concerns
Study Details
Access Study
Disclosures
Funding
Not reported
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.