meta_analysis
2016
High Quality
A meta-analysis on the efficacy and safety of St John's wort extract in depression therapy in comparison with selective serotonin reuptake inhibitors in adults
Zheng Y, Cui Y
Published in Neuropsychiatric Disease and Treatment
Methodology
Meta-analysis of randomized head-to-head trials of Hypericum extract versus SSRIs in adults with depression.
Key Findings
No significant difference in efficacy versus SSRIs; adverse events were significantly less frequent with Hypericum.
Conclusions
Hypericum extract is an effective and better-tolerated alternative to SSRIs in adult depression.
Limitations
Included trials mostly enrolled mild to moderate cases; publication bias possible.
Supplements Studied
St. Johns Wort
Herb
Hypericum extract is an effective and better-tolerated alternative to SSRIs in adult depression.
Related Health Concerns
Study Details
Year:2016
Quality Score:7/10
Access Study
This information is for educational purposes only. Always consult a healthcare professional before starting any supplement regimen.