rct
2006
High Quality
Prevention of Syncope Trial (POST): a randomized, placebo-controlled study of metoprolol in the prevention of vasovagal syncope
Sheldon R, Connolly S, Rose S, Klingenheben T, Krahn A, Morillo C, Talajic M
Published in Circulation
Key Findings
Metoprolol did not reduce recurrence of syncope compared with placebo over one year.
Conclusions
Beta-blockers are not effective for preventing fainting in the general vasovagal population.
Limitations
Possible benefit in older subgroups not confirmed here.
Related Health Concerns
Study Details
Year:2006
Sample Size:208
Duration:52 weeks
Quality Score:9/10
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