Vitamin D deficiency in alopecia areata: a systematic review and meta-analysis
Lee S, Kim BJ, Lee CH, Lee WS
Published in Journal of the European Academy of Dermatology and Venereology
Methodology
Systematic review and meta-analysis of 14 observational studies comparing serum 25-hydroxyvitamin D between alopecia areata patients and controls.
Key Findings
Alopecia areata patients had significantly lower serum vitamin D levels and higher odds of deficiency than controls.
Conclusions
Vitamin D deficiency is associated with alopecia areata, though causality and the benefit of supplementation remain unproven.
Limitations
Observational studies only; reverse causation possible; no supplementation trials included.
Supplements Studied
Alopecia areata patients had significantly lower serum vitamin D levels and higher odds of deficiency than controls.
Outcomes Measured
Alopecia areata patients had significantly lower serum vitamin D and higher odds of deficiency than controls.
Related Health Concerns
Study Details
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